Publications by authors named "L Tung"
Article Synopsis
- Quantum dots (QDs) are small semiconductor particles that could improve biomedical imaging and drug delivery, with Indium phosphide QDs covered by zinc sulphide being a more biocompatible option.
- This study reveals that PEGylating these QDs significantly reduces platelet activation and aggregation, which is important to prevent excessive blood clotting.
- By decreasing the interaction between QDs and platelets, PEGylation enhances the safety and effectiveness of QDs for use in medical applications.
Background: Arrhythmogenic cardiomyopathy (ACM) is a genetic disorder responsible for nearly a quarter of sports-related sudden cardiac deaths. ACM cases caused by mutations in desmosome proteins lead to right ventricular enlargement, the loss of cardiomyocytes, and fibrofatty tissue replacement, disrupting electrical and mechanical stability. It is currently unknown how paracrine factors secreted by infiltrating fatty tissues affect ACM cardiomyocyte electrophysiology.
View Article and Find Full Text PDFUnlabelled: Human induced pluripotent stem-cell derived cardiomyocytes (hiPSC-CMs) have proven to be a revolutionary advance for tissue engineering, disease modeling, and drug testing and discovery. Computational modeling enables a detailed electrophysiological analysis that is otherwise difficult or impossible to achieve under strictly experimental settings. Action potential characteristics of hiPSC-CMs measured in our lab at four different pacing rates were used it to modify the computational Kernik-Clancy hiPSC-CM model.
View Article and Find Full Text PDFIntroduction: In Viet Nam, key populations (KPs) face barriers accessing HIV services. Virtual platforms can be leveraged to increase access for KPs, including for HIV self-testing (HIVST). This study compares reach and effectiveness of a web-based HIVST intervention from pilot to scale-up in Viet Nam.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigated the effects of behavioral therapy on dysphagia in 230 acute ischemic stroke patients receiving nasogastric tube feeding, comparing a normal care group with a group that participated in daily swallowing exercises for about 60 minutes.
- - Researchers used the Gugging Swallowing Screen (GUSS) to assess dysphagia and applied a difference-in-differences (DID) method to analyze the effectiveness of the therapy.
- - Findings indicated that behavioral therapy significantly improved swallowing abilities in stroke patients, suggesting it as a valuable approach for dysphagia rehabilitation.