[MIELIN BASIC PROTEIN IN THE BRAIN TISSUE OF THE BALB/C MICE WITH EXPERIMENTAL ANTIPHOSPHOLIPID SYNDROME AND AFFECTION WITH NITRIC OXIDE SYNTHESIS MODULATORS].

The aim of the research was to study the content of myelin basic protein (MBP) in the cerebellum and cerebral hemispheres of the BALB/c mice with experimental antiphospholipid syndrome as well as in cases of introduction of L-arginine and aminoguanidine. The research was performed using 50 female BALB/c mice, in which APS was simulated. L-arginine (25 mg/kg) and aminoguanidine (10 mg/kg) were used for correction.

[Problem of mineral insufficiency at chronic pancreatitis in dependence on age].

The high incidence of chronic pancreatitis (CP) which arise at young people of working age, the development of serious complications are pushing for the development of new diagnostic methods and the search for effective ways to treat this disease. In this regard, a relevant and promising direction is the further study of the mechanisms of pathogenesis and the formation of trophological (including mineral) deficiency in CP, followed by the development of comprehensive programs for their correction. is to study mineral status of patients with chronic pancreatitis, depending on their age.

The effect of the proteolisis' system activity for the trophological status of patients with osteoarthrosis and excretory insufficiency of pancreas.

Objective: Introduction:The excretory insufficiency of pancreas in patients with primary osteoarthrosis is formed at the comorbid pathologies and as a result of long-term treatment of osteoarthrosis using the non-steroidal anti-inflammatory drugs, steroids, chondroprotectors and chondrostimulators etc. The aim: to study the state of the proteolysis system and immune status, the presence and depth of the dysbiosis of colon in patients with primary osteoarthrosis against a violation of their excretory insufficiency of pancreas.

Patients And Methods: Materials and methods: There were 64 outpatients with primary OA (group 1) and 74 patients with primary OA in combination with diseases associated with EIP (group 2).

Clinico-pathogenic aspects of osteodeficiency in osteoarthritis in combination with chronic pancreatitis.

Objective: Introduction: Pathology of the musculoskeletal system creates a number of important and complex medical problems affecting the economic situation of society, health and quality of life of individuals and their families. One of these problems and the most common disease of the joints which is diagnosed in 20% of the population of the planet is osteoarthritis (OA). The aim: The article deals with modern views on the problem of comorbidity of osteoarthritis, chronic pancreatitis and osteodefiсiency.