Vaping guidance and women's decision-making during pregnancy & postpartum.

Background: Vaping during pregnancy remains under researched and under reported, making appropriate prevention, health promotion and intervention difficult to design and mount. In this article we assessed the experiences and considerations of women who vape during pregnancy and/or within 2 years post-partum, in order to underpin realistic and informative health information for women and providers in face of conflicting and minimal guidance.

Design: 22 interviews were conducted with pregnant and post-partum women who vape(d) nicotine, cannabis, or both during pregnancy and/or after delivery.

The nucleolin antagonist N6L and paclitaxel combination treatment could be a new promising therapeutic strategy for pancreatic ductal adenocarcinoma therapy.

Pancreatic cancer (PCa) is one of the most devastating cancers with few clinical signs and no truly effective therapy. In recent years, our team has demonstrated that nucleolin antagonists such as N6L could be a therapeutic alternative for this disease. In order to study a possible clinic development of N6L (multivalent pseudopeptide), we undertook to study the effect of combination of N6L with chemotherapies classically used for PCa on the survival of pancreatic cancer cells.

3D modeling to predict vascular involvement in resectable pancreatic adenocarcinoma.

Background: Current management of patients with borderline resectable pancreatic adenocarcinoma (BR-PDAC) depends on the degree of involvement of the major arterial and venous structures. The aim of this study was to evaluate 3D segmentation and printing to predict tumor size and vascular involvement of BR-PDAC to improve pre-operative planning of vascular resection and better select patients for neoadjuvant therapy.

Methods: We retrospectively evaluated 16 patients with BR-PDAC near vascular structures who underwent pancreatoduodenectomy (PD) with or without vascular resection between 2015 and 2021.

An Interesting Case of Vitamin D-Mediated Severe Hypercalcemia in a Patient With Renal Mass.

Hypercalcemia of malignancy (HCM) is the most common cause of hypercalcemia in hospitalized patients. The pathogenesis of HCM is often multifactorial. One of the rare causes of HCM is extra-renal production of 1,25-dihydroxyvitamin D (or calcitriol), which is often seen in patients with lymphoproliferative malignancies.

Increased BMI is associated with an altered decision-making process during healthy food choices in males and females.

Unhealthy diets (rich in calories, sugar, fat, and sodium) are a major cause of obesity. Why individuals struggle to make healthy food choices remains unclear. This study examined how body mass index, biological sex, and eating context influence food attribute perception, the food choice process, and the percentage of healthy food choices.