COVID for One: Identifying Obstacles to Self-Management of COVID-19 for Single Adults.

Given the complexities of healthcare provision, it is imperative to understand how single adults experience their interactions with medical professionals and health care organizations, manage care and treatment, and navigate the barriers encountered. This study's purpose is to understand physical and mental health experiences in consideration of social determinants of health, barriers, and coping strategies for single adults diagnosed with COVID-19. An interpretive phenomenology study design was used with 12 individuals who were single and living alone during the COVID-19 pandemic.

Formal synthesis of kibdelomycin and derivatisation of amycolose glycosides.

A convergent total synthesis of bacterial gyrase B/topoisomerase IV inhibitor kibdelomycin (a.k.a.

Dynamics of Above-Threshold Ionization and Laser-Assisted Electron Scattering inside Helium Nanodroplets.

Laser-assisted electron scattering (LAES) is a fundamental three body interaction process that enables energy transfer between electrons and photons in the presence of matter. Here, we focus on the multiscattering regime of electrons generated by above-threshold ionization (ATI) of In atoms inside a high-density nanostructure, helium nanodroplets (He) of ∼40 Å radius. The stochastic nature of the multiscattering regime results in photoelectron spectra independent of laser polarization.

Post-traumatic stress disorder following childbirth: prevalence and associated factors-a prospective cohort study.

Objective: Traumatic experiences during or after childbirth are subject of intense discussions in mainstream and social media as well as in scientific literature. Aim of this evaluation is to estimate the prevalence of post-traumatic stress disorder (PTSD) following childbirth in postpartum women and to evaluate the influence of maternal, obstetrical and neonatal characteristics on the degree of PTSD symptoms measured by the Impact of Events Scale questionnaire (IES-R).

Methods: In total, 589 women who gave birth in the University Medical Center Mainz, Germany in 2016, participated in a survey within the first days after birth.

Dual Agents: Fungal Macrocidins and Synthetic Analogues with Herbicidal and Antibiofilm Activities.

Eight analogues of the bioherbicides macrocidin A () and Z () with structural variance in the size of the macrocycle, its - or -cyclophane character, and its functional groups were synthesized on two modular routes and tested for herbicidal, antibiotic, and antibiofilm activities. Apart from the lead compounds and , the structurally simplified dihydromacrocidin Z () and normacrocidin Z () showed high herbicidal activity in either thistles, dandelions or in both. The derivatives , , and dibromide also inhibited the growth of biofilms by ca 70% when applied at subtoxic concentrations as low as ca 20 µM, which are unlikely to induce bacterial resistance.