Publications by authors named "L Townsley"

Radiative and mechanical feedback of massive stars regulates star formation and galaxy evolution. Positive feedback triggers the creation of new stars by collecting dense shells of gas, while negative feedback disrupts star formation by shredding molecular clouds. Although key to understanding star formation, their relative importance is unknown.

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Article Synopsis
  • c-di-GMP is a crucial second messenger in bacteria that regulates cell attachment during biofilm formation by controlling the expression and surface display of adhesins.
  • Researchers identified a conserved system regulating adhesin stability in Vibrio cholerae, revealing how c-di-GMP influences two classes of adhesins necessary for attachment and biofilm development.
  • Understanding this regulatory mechanism may lead to strategies to disrupt biofilm formation, which is vital for V. cholerae's survival and infectivity.
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There is a growing appreciation for the impact that bacteria have on higher organisms. Plant roots often harbor beneficial microbes, such as the Gram-positive rhizobacterium , that influence their growth and susceptibility to disease. The ability to form surface-attached microbial communities called biofilms is crucial for the ability of to adhere to and protect plant roots.

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Cell-cell communication enables bacteria to coordinate their behavior through the production, recognition, and response to chemical signals produced by their microbial neighbors. An important example of coordinated behavior in bacteria is biofilm formation, where individual cells organize into highly complex, matrix-encased communities that differentiate into distinct cell types and divide labor among individual cells. Bacteria rely on environmental cues to influence biofilm development, including chemical cues produced by other microbes.

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Bacillus luciferensis is a Gram-positive, facultatively anaerobic, motile rod. Here, we report the first draft genome sequence, to our knowledge, of a B. luciferensis strain (CH01), which will provide useful information for Bacillus and soil bacteria research.

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