Publications by authors named "L Tonnetti"
Article Synopsis
- The WHO African Region is significantly impacted by malaria, contributing to 94% of global cases, prompting research on detecting Plasmodium RNA in blood donors from Cameroon, Madagascar, and Mali.
- Testing involved analyzing whole blood samples using a specialized assay to identify reactive results, with findings revealing varying rates of Plasmodium repeat reactivity across the countries.
- The study concluded that detecting Plasmodium RNA and related antibodies can enhance safety measures in blood donations and help tackle malaria risks effectively.
Objectives: Human babesiosis is an emerging and potentially fatal tick-borne disease caused by intraerythrocytic parasites of the Babesia genus. Among these, Babesia duncani is particularly notable for causing severe and life-threatening illness in humans. Accurate diagnosis and effective disease management hinge on the detection of active B.
View Article and Find Full Text PDFBackground And Objectives: Trypanosoma cruzi is the etiologic agent of Chagas disease (CD), an anthropozoonosis from the American continent that progresses from an acute phase to an indeterminate phase, followed by a chronic symptomatic phase in around 30% of patients. In countries where T. cruzi is not endemic, many blood transfusion services test blood donors who have stayed in an endemic country ('at-risk stay')-even if they do not present with other risk factors.
View Article and Find Full Text PDFUnlabelled: Human babesiosis is a rapidly emerging and potentially fatal tick-borne disease caused by intraerythrocytic apicomplexan parasites of the genus. Among the various species of that infect humans, has been found to cause severe and life-threatening infections. Detection of active infection is critical for accurate diagnosis and effective management of the disease.
View Article and Find Full Text PDFBackground: Anaplasma phagocytophilum is a tick-borne bacterium and the cause of human granulocytic anaplasmosis (HGA). Here, we report a case of transfusion-transmitted (TT)-HGA involving a leukoreduced (LR) red blood cell (RBC) unit.
Case Report: A 64-year-old woman with gastric adenocarcinoma and multiple myeloma who received weekly blood transfusions developed persistent fevers, hypotension, and shortness of breath 1 week after receiving an RBC transfusion.