Publications by authors named "L Tondo"
Affective temperaments: Effects on treatment response for major depression.
Asian J Psychiatr
November 2024
There is growing interest in assessing affective temperaments in relation to major depressive disorder (MDD) and bipolar disorder (BD). Needed is evaluation of the impact of temperament ratings on responses to treatment of depression in these disorders. We measured treatment response as %-improvement in HDRS depression ratings and correlated this measure as well as response rate (≥50 % improvement) with TEMPS-A ratings of anxious, cyclothymic, dysthymic, hyperthymic, and irritable affective temperaments in 2264 mood-disorder patients (1165 BD, 1099 MDD; 62.
View Article and Find Full Text PDFBackground: Whether responses to treatment of major depressive episodes differ between women and men or with bipolar (BD) and major depressive disorders (MDD) remains unresolved.
Aims: To test for diagnostic and sex differences in responses to treatment of depression.
Methods: We compared changes in the 21-item Hamilton Depression Rating Scale (HDRS) ratings of depression ( = 3243) between women (64.
Article Synopsis
- Bipolar disorder (BD) is a complex mental health condition, and researchers aimed to identify a neurodevelopmental phenotype (NDP) that contributes to its development and impacts clinical outcomes.
- By analyzing data from over 4,400 BD patients, they established nine specific clinical features that characterize this NDP, which are linked to poorer prognosis and treatment responses.
- The findings suggest that patients with a higher NDP load may have overlapping genetic factors with ADHD, indicating a potential shared biological basis for these disorders.