Publications by authors named "L Tomasevic"

Transcranial magnetic stimulation (TMS) triggers time-locked cortical activity that can be recorded with electroencephalography (EEG). Transcranial evoked potentials (TEPs) are widely used to probe brain responses to TMS. Here, we systematically reviewed 137 published experiments that studied TEPs elicited from TMS to the human primary motor cortex (M1) in healthy individuals to investigate the impact of methodological choices.

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Background: Transcranial evoked potentials (TEPs) measured via electroencephalography (EEG) are widely used to study the cortical responses to transcranial magnetic stimulation (TMS). Immediate transcranial evoked potentials (i-TEPs) have been obscured by pulse and muscular artifacts. Thus, the TEP peaks that are commonly reported have latencies that are too long to be caused by direct excitation of cortical neurons.

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Article Synopsis
  • Quantum sensors using solid state qubits, particularly those based on diamond colour centres, have shown exceptional sensitivity to magnetic fields, making them suitable for biological applications.
  • This study successfully utilized a quantum sensor to non-invasively record electrical activity from neurons in living brain tissue, specifically tracking ionic currents in mouse axons.
  • The passive and remote nature of this sensing technique allows for a new method to understand neuronal circuits and disease mechanisms, possibly leading to future advancements in imaging brain activity in live mammals.
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Efficient interhemispheric integration of neural activity between left and right primary motor cortex (M1) is critical for inter-limb motor control. We employed optogenetic stimulation to establish a framework for probing transcallosal M1-M1 interactions in rats. We performed optogenetic stimulation of excitatory neurons in right M1 of male Sprague-Dawley rats.

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