Publications by authors named "L Tikhomirova"
Article Synopsis
- The study measured the electrical impedance and pulsation ranges of brachial and femoral arteries in rats after 14 days of hindlimb unloading (a model for microgravity).
- Results showed that the femoral artery constricted while the brachial artery dilated, with both exhibiting reduced pulsation dynamics.
- The ability of the femoral artery to switch to an active pulsatile mode during bloodletting was significantly lower in unloaded rats than in control rats, indicating potential negative effects of microgravity on blood circulation.
Article Synopsis
- The study investigated the pulsation patterns of the femoral and carotid arteries in rats during acute blood loss and observed significant changes as blood pressure (BP) dropped.
- When BP fell to critical levels, the arteries exhibited increased mechanosensitivity and changed their pulsing mode from passive to active, responding to systolic changes in BP.
- The findings support the "transarterial hypotensive transition hypothesis," suggesting that the behavior of major arteries during drastic BP drops resembles that of smaller arterioles, highlighting a refined understanding of the "peripheral heart" in hypertension and hypotension.
In experiments on narcotized male rats (n=85), the mean electroimpedance Z and peak-to-peak magnitudes (the swing ranges) of passive (ΔZ) and active (ΔZ) pulsatile electroimpedance oscillations of isolated segment of femoral arteries were determined in situ. These rheographic parameters (RP) were measured in intact animals and in those with modeled chronic myocardial infarction, chronic denervation of the right hind leg, as well as in rats subjected to sham operations to mimic denervation or infarction (with thoracic trauma). The rats with modeled myocardial infarction demonstrated decreasing trends of all RP.
View Article and Find Full Text PDFIntroduction: Iris L. are promising in medicine due to the biological activity of extracts. Iris sibirica L.
View Article and Find Full Text PDF[The determining factors of qualitative training of students in public health and health care].
Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med
July 2021
The inclusion of public health and health care measures in labor functions of professional standards of medical specialists increased significance of mastering of these standards by students during specialty training, since on this depends their successful completion of primary accreditation of specialists and implementation of job descriptions in the course of daily activities. The purpose of the study was to analyze factors determining qualitative of mastering the discipline "Public health and Health Care" by students of medical educational organizations. The analytical, logical, statistical, questionnaire survey and direct ranking methods were applied.
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