Publications by authors named "L Theron-Gerard"

Article Synopsis
  • Serum testosterone levels may not be the best indicator for assessing ovarian response to FSH during IVF, as seen in the study of infertile women.
  • The study measured various androgen levels before and after a stimulation test, finding that 17-hydroxyprogesterone (17-OHP) had the strongest correlation with the number of follicles and ovarian reserve.
  • The results suggest that post-stimulation serum 17-OHP levels could serve as a better predictor of ovarian responsiveness to IVF compared to testosterone levels.
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The link between hypothyroidism and infertility is still a matter of debate. Hypothyroidism can result in cycle disturbances, such as oligomennorhea and functional bleeding. Additionally, several studies have shown that thyroid autoimmunity (detection of anti peroxydase antibodies) may account for the occurrence of repetitive miscarriages.

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The FSH receptor presents several polymorphisms. Two of them, located at codon 307 and 680, are the most frequent. Threonine can be substituted by alanine at position 307 and serine can be substituted by asparagine at position 680.

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Polycystic ovary syndrome is a frequent endocrine disorder often associated with insulin resistance and hyperinsulinaemia which may play a role in hyperandrogenism and anovulation. The use of "insulin sensitizing" agents has been suggested to reduce insulin resistance and hyperandrogenism. In that respect, the use of metformin in polycystic ovary syndrome is reviewed.

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