Endocrine mechanisms underlying the growth effects of developmental lead exposure in the rat.

A dose-response study was conducted to examine the growth suppression associated with developmental lead exposure in a rat model and to determine the endocrine mechanisms underlying these effects. Ad libitum intake of lead acetate (0.05% to 0.

Peripheral endocrine and metabolic responses to centrally administered interleukin-1.

It is becoming increasingly apparent that interleukin-1 (IL-1) acts systemically and centrally to play an important role in regulating the hormonal and metabolic response to stress, infection, and trauma. The aim of this study was to observe the peripheral metabolic and endocrine responses to 15, 25, and 50 ng intracerebroventricular (i.c.