Publications by authors named "L Tappy"
Article Synopsis
- Roux-en-Y gastric bypass (RYGB) surgery can cause post-bariatric hypoglycaemia (PBH) due to changes in glucose handling by the liver.
- A study compared RYGB patients with PBH to healthy controls by tracking glucose and hormone levels after consuming glucose, using advanced imaging techniques.
- Results showed that RYGB patients had distinct glucose and insulin responses, including a quicker rise and fall in glucose levels and lower sensitivity to insulin, but did not have impaired liver glucose uptake or output contributing to PBH.
Background: Chronic exposure to high iron levels increases diabetes risk partly by inducing oxidative stress, but the consequences of acute iron administration on beta cells are unknown. We tested whether the acute administration of iron for the correction of iron deficiency influenced insulin secretion and the production of reactive oxygen species.
Methods: Single-center, double-blinded, randomized controlled trial conducted between June 2017 and March 2020.
Following a request from five European Nordic countries, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was tasked to provide scientific advice on a tolerable upper intake level (UL) or a safe level of intake for dietary (total/added/free) sugars based on available data on chronic metabolic diseases, pregnancy-related endpoints and dental caries. Specific sugar types (fructose) and sources of sugars were also addressed. The intake of dietary sugars is a well-established hazard in relation to dental caries in humans.
View Article and Find Full Text PDFDietary carbohydrates are our main source of energy. Traditionally, they are classified based on the polymer length between simple and complex carbohydrates, which does not necessarily reflect their impact on health. Simple sugars, such as fructose, glucose, and lactose, despite having a similar energy efficiency and caloric content, have very distinct metabolic effects, leading to increased risk for various chronic diseases when consumed in excess.
View Article and Find Full Text PDFBackground: Both fructose consumption and chronic stress contribute to the development of metabolic disorders. The consequences of such combination are not fully understood.
Objective: We investigated whether fructose supplementation and chronic stress synergistically disturb hepatic lipid and glucose metabolism.