Publications by authors named "L T Yeng"
In this randomized, double-blind, parallel placebo-controlled clinical trial, we evaluated the efficacy of methadone as an add-on therapy for people with chronic neuropathic pain (NP). Eighty-six patients were randomly assigned to receive methadone or placebo for 8 weeks. The primary outcome was the proportion of participants achieving at least 30% pain relief from baseline using a 100-mm pain Visual Analogue Scale.
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- - This study investigated trigger points (TPs) in twelve military police working dogs, focusing on their locations and prevalence after intense physical activity, using standardized palpation techniques by independent examiners.
- - The highest percentage of TPs was found in the lumbar muscles (42%), with a significant number also in the hind limb muscles, predominantly on the right side of the body.
- - The results aim to improve understanding of myofascial pain in working dogs, potentially leading to better pain management strategies and reducing premature retirements caused by musculoskeletal issues.
Objectives: It is not known whether cortical plastic changes reported in low-back pain (LBP) are present in all etiologies of LBP. Here we report on the assessment of patients with three LBP conditions: non-specific-LBP (ns-LBP), failed back surgery syndrome (FBSS), and sciatica (Sc).
Methods: Patients underwent a standardized assessment of clinical pain, conditioned pain modulation (CPM), and measures of motor evoked potential (MEPs)-based motor corticospinal excitability (CE) by transcranial magnetic stimulation, including short interval intracortical inhibition (SICI), and intracortical facilitation (ICF).
Objectives: Central neuropathic pain (CNP) is associated with altered corticomotor excitability (CE), which can potentially provide insights into its mechanisms. The objective of this study is to describe the CE changes that are specifically related to CNP.
Methods: We evaluated CNP associated with brain injury after stroke or spinal cord injury (SCI) due to neuromyelitis optica through a battery of CE measurements and comprehensive pain, neurological, functional, and quality of life assessments.
Article Synopsis
- The study aims to understand how different types of central nervous system injuries can affect the way central neuropathic pain (CNP) presents in patients.
- Researchers compared pain profiles between patients with central post-stroke pain (CPSP) and those with spinal cord injury pain (CPSCI), observing significant differences in pain scores and sensory responses.
- The results indicate that the location of the brain or spinal cord injury may influence pain sensations and thresholds, suggesting that tailored treatment strategies could be developed based on these differences in CNP profiles.