Publications by authors named "L T Toĭvonen"
Study Design: Cohort study.
Objective: To evaluate heterogeneity (fluctuation) in minimal important change (MIC) and patient-acceptable symptom state (PASS) for patient-reported outcomes (PROMs) through 10 years after lumbar fusion.
Summary Of Background Data: PROMs have become key determinants in spine surgery outcomes studies.
Background: Comparative data are limited on the transmission of respiratory infections positive and negative for SARS-CoV-2 in households with children.
Methods: In June to August 2020, we recruited 700 participants (175 households, 376 children, 324 adults) to be prospectively followed for all respiratory tract infections. Follow-up lasted from recruitment until April 2022.
The ST2/IL-33 signaling pathway has an important role in the host inflammatory response. Here we aimed to study the association of ST2 and IL-33 polymorphisms with serum soluble (s) ST2 and IL-33 concentrations in healthy Finnish children and, in addition, their association with childhood asthma. In total, 146 children were followed from birth to the age 7 years for the development of asthma.
View Article and Find Full Text PDFStudy Design: Retrospective analysis of prospectively collected data.
Objective: To evaluate how preexisting adjacent segment degeneration status impacts revision risk for adjacent segment disease (ASD) after lumbar fusions.
Summary Of Background Data: ASD incurs late reoperations after lumbar fusion surgeries.
Background Context: Lumbar spine fusion (LSF) surgery is a viable form of treatment for several spinal disorders. Treatment effects are preferably to be endorsed in real-life settings.
Methods: This prospective study evaluated the 10-year outcomes of LSF.