Effect of cord blood cells on interferonogenesis and effector cells of immune system.

Human cord blood cells were shown to produce interferon-alpha- and -gamma in vitro, both spontaneously and following adequate induction. Transplantation of human blood cord cells to mice led to endogenous interferonogenesis activation, serum interferon levels as well as interferon-alpha and interferon-gamma synthesis by activated peripheral blood leucocytes becoming higher. The maximal interferon accumulation in murine blood sera following transplantation did not coincide with interferonogenesis dynamics observed due to the effect of standard early and late interferon inducers - poly I:C and ridostin, respectively.

[Effect of acute hemorrhage on hemostasis in dogs not adapted to high-altitude conditions].

Acute blood loss was easier after 3-day stay high in the mountains than after a stay in a low place. This is explained by increased blood fibrinolytic activity and high blood antithrombin level recorded by the third day of the animals' stay in the mountains.