Primary care transformation in Scotland: a comparison two cross-sectional national surveys of general practitioners' views in 2018 and 2023.

Background: The 2018 Scottish GP contract established GP Clusters and multidisciplinary team (MDT) expansion. Qualitative studies have suggested sub-optimal progress.

Aim: To quantify progress since the introduction of the new contract.

Characteristics and outcomes of patients with repeat rapid response team activations in a tertiary centre in Singapore.

Introduction: Rapid response teams (RRTs) are prevalent in healthcare institutions worldwide. Repeated activations are associated with increased morbidity and higher resource utilisation, and represent a heterogeneous population that may benefit from early identification. To date, there are no published data on repeat RRT activations in Singapore.

Peer Mentoring by Medical Students for Medical Students: A Scoping Review.

Medical school transitions pose challenges for students. Mentoring programs may aid students, but evidence supporting peer/near-peer mentoring in medical school is unclear. Our review explores peer mentoring's benefits, elements for success and challenges.

The effect of responsible leadership on organizational citizenship behavior: double mediation of gratitude and organizational identification.

Background: Organizational citizenship behavior (OCB) is a non-compulsory but beneficial behavior for effective organizational operation. OCB can be largely determined by the type of leadership style, among which responsible leadership has been attracting considerable attention in the organizational context nowadays. The objective of this study was to examine the parallel mediating effect of gratitude and organizational identification between responsible leadership and OCB among the academic staff in China.

Effects of RARα ligand binding domain mutations on breast fibroepithelial tumor function and signaling.

Point mutations in the ligand binding domain of retinoic acid receptor alpha (RARα) are linked to breast fibroepithelial tumor development, but their role in solid tumorigenesis is unclear. In this study, we assessed the functional effects of known RARα mutations on retinoic acid signaling using biochemical and cellular assays. All tested mutants exhibited reduced transcriptional activity compared to wild-type RARα and showed a dominant negative effect, a feature associated with developmental defects and tumor formation.