Navigating professional growth for women in radiology: A practical guide for mentorship, sponsorship, and coaching.

Historically, women in radiology are underrepresented in radiology and face disproportionate barriers to career advancement related to work-life integration, gender bias, and relative lack of female role models. Given these challenges, women must be proactive and seek out mentorship and sponsorship to help navigate career obstacles and to guide career direction. At times of inflection, coaching can play a role in helping to clarify next steps through self-discovery of one's strengths, limitations, and desired goals.

Clinical and Imaging Features Associated With Malignant Focal Nonmass Enhancement on Breast MRI.

Introduction: Focal non-mass enhancement (NME) is a common breast MRI finding with limited data to guide management. This study aimed to assess clinical and imaging features of malignant BI-RADS 4 focal NME.

Methods: This IRB-approved, retrospective study included breast MRI exams between August 1, 2013 and September 1, 2022 yielding BI-RADS 4 focal NME lesions that underwent core biopsy or excision with available pathology result or demonstrated decrease or resolution during follow-up MRI or at least 2 years of MRI stability.

HIF1α-regulated glycolysis promotes activation-induced cell death and IFN-γ induction in hypoxic T cells.

Hypoxia is a common feature in various pathophysiological contexts, including tumor microenvironment, and IFN-γ is instrumental for anti-tumor immunity. HIF1α has long been known as a primary regulator of cellular adaptive responses to hypoxia, but its role in IFN-γ induction in hypoxic T cells is unknown. Here, we show that the HIF1α-glycolysis axis controls IFN-γ induction in both human and mouse T cells, activated under hypoxia.

Pandemic Exercises: Lessons for a New Era in Pandemic Preparedness.

We led the last large-scale exercise conducted by the Johns Hopkins Center for Health Security before the COVID-19 pandemic. Despite COVID-19, pandemic exercises are more necessary than ever to prevent the loss of hard-fought gains achieved during COVID-19, keep policymakers from assuming all pandemics will be like COVID-19, and encourage continued engagement from policymakers in strengthening health resilience rather than returning to a cycle of panic and neglect. Pandemic exercises can also advance new solutions necessary to effectively meet the challenge of a future pandemic.