[The action of bemitil on the self-regulation systems during short-term immobilization].

In the immobilized rats bemithyl (50 mg/kg in a single dose) was shown to normalize the state of the musculomotor and cardiovascular systems exerting the positive influence on the key links of the process of autoregulation in the form of the sedative (the central nervous system), stress-protective (hormonal regulation) and antihypoxic (metabolism) effects that characterizes it as the drug with the distinct antistress activity.

[The use of melipramine in treating patients with a depressive syndrome accompanied by motor retardation].

A study of 49 patients with the depressive syndrome and showing different motor activity indicates that melipramin treatment proved more effective during the first week of treatment. The obtained data are confirmed by results of experiments with immobilized animals.