Publications by authors named "L T C Sally Harvey"

The nutritional environment during fetal and early postnatal life has a long-term impact on growth, development, and metabolic health of the offspring, a process termed "nutritional programming." Rodent models studying programming effects of nutritional interventions use either purified or grain-based rodent diets as background diets. However, the impact of these diets on phenotypic outcomes in these models has not been comprehensively investigated.

View Article and Find Full Text PDF
Article Synopsis
  • Delirium is a common complication for older adults after hip fracture surgery, with a study analyzing patient data from 2015-2020 revealing inconsistent links between the type of anaesthesia used and the occurrence of delirium.
  • Among the 35,252 patients studied, those who received general anaesthesia (40.6%) showed higher rates of delirium compared to those who received spinal or regional anaesthesia (35.7%).
  • Adjustments for known confounders indicated a weak association between general anaesthesia and delirium, but an analysis addressing unmeasured factors found no significant causal link, suggesting more research is needed in this area.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the incidence and outcomes of hypothermic cardiac arrest (HCA) in an urban setting, contrasting with previous focus on wilderness cases.
  • Among 171 eligible patients, 25% suffered HCA, with risk increasing significantly as core temperature decreased; HCA was seen in 6% of moderately hypothermic, 38% of severely hypothermic, and 89% of profoundly hypothermic patients.
  • Witnessed HCA cases, particularly in prehospital or emergency department settings, showed favorable survival outcomes, with a 53% overall survival rate, and even higher (90%) for patients whose HCA occurred post-arrival in the ED.
View Article and Find Full Text PDF

Question: Is electrical stimulation (ES) combined with strength training and usual care more effective than usual care alone in increasing the strength of very weak muscles in people with recent spinal cord injury (SCI)?

Design: A randomised controlled trial with concealed allocation, intention-to-treat analysis and blinded outcome assessors.

Participants: Sixty participants with recent SCI were recruited from three SCI units in Australia and Bangladesh.

Interventions: Participants were randomised to either a treatment or control group.

View Article and Find Full Text PDF