Publications by authors named "L T Araujo Janahu"
Neuroimmunomodulation
October 2021
Article Synopsis
- - HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive disease linked to inflammation in the central nervous system, where HTLV-1-infected T cells enhance their migration by altering adhesion receptor expression.
- - The study examined the presence of three specific integrin alpha chains on T cells in both HAM/TSP patients and asymptomatic individuals, finding increased levels of CD49dhi CD4+ and CD49dhi CD8+ T cells in those infected with HTLV-1.
- - The results indicate that elevated CD49d expression on T lymphocytes may play a role in disease development, suggesting that targeting CD49d could potentially prevent the migration of
