Proving the automatic benchtop electrochemical station for the development of dopamine and paracetamol sensors.

The introduced work represents an implementation of the automatic benchtop electrochemical station (BES) as an effective tool for the possibilities of high-throughput preparation of modified sensor/biosensors, speeding up the development of the analytical method, and automation of the analytical procedure for the determination of paracetamol (PAR) and dopamine (DOP) as target analytes. Within the preparation of gold nanoparticles modified screen-printed carbon electrode (AuNPs-SPCE) by electrodeposition, the deposition potential E, the deposition time t, and the concentration of HAuCl were optimized and their influence was monitored on 1 mM [Ru(NH)] redox probe and 50 μM DOP. The morphology of the AuNPs-SPCE prepared at various modification conditions was observed by SEM.

Nano-size cobalt-doped cerium oxide particles embedded into graphitic carbon nitride for enhanced electrochemical sensing of insecticide fenitrothion in environmental samples: An experimental study with the theoretical elucidation of redox events.

In the present work, a nanocomposite, based on embedding Co-doped CeO nanoparticles into graphitic carbon nitride (g-CN), was applied to functionalize commercial glassy carbon paste. This is the first application of the electrochemical sensor, developed through the proposed procedure, in electrochemical sensing. The sensor was utilized for the electrochemical determination of organophosphate pesticide fenitrothion (FNT).

Electrochemical flow injection approach for routine screening of lipase activity in pancreatic preparations.

A state-of-the-art strategy for the determination of lipase activity in pancreatic preparations using flow injection analysis (FIA) with electrochemical detection (FIA-ED) is described. The procedure is based on the enzymatic reaction of a specific substrate (1,3-dilinoleoyl-glycerol) with lipase from porcine pancreas and determination of enzymatically formed linoleic acid (LA) at +0.4 V by applying a cobalt (II) phthalocyanine-multiwalled carbon-nanotubes modified carbon paste electrode (Co(II)PC/MWCNT/CPE).

Batch injection analysis in tandem with electrochemical detection: the recent trends and an overview of the latest applications (2015-2020).

The purpose of the proposed review is to refer the contemporary capability of automated analytical systems, in particular batch injection analysis (BIA) in connection with electrochemical detection, for widespread applications in analytical chemistry. This combination recently represents an efficient tool for improvement of method parameters, such as speed, selectivity, and sampling rate for sensing of miscellaneous organic and inorganic substances. The review is focused on conception and usage of BIA in tandem with electrochemical detection utilizing various techniques, namely amperometry, voltammetry, and multiple pulse amperometry, as well as design of electrochemical cells constructed for BIA systems is discussed.

In vitro biological activity of copper(II) complexes with NSAIDs and nicotinamide: Characterization, DNA- and BSA-interaction study and anticancer activity.

Through the reaction of copper(II) acetate with nicotinamide (pyridine-3-carboxylic acid amide, niacinamide) and some derivatives of N-phenylanthranilic acid (fenamates), seven new mixed-ligand copper(II) compounds were isolated: [Cu(tolf-O)(tolf-O,O')nia-N)(EtOH)] (1), [Cu(tolf-O)(tolf-O,O')(nia-N)(MeOH)] (2), [Cu(meclf-O)(meclf-O,O')(nia-N)(EtOH)] (3), [Cu(meclf-O)(meclf-O,O')(nia-N)(MeOH)] (4), [Cu(meclf-O)(meclf-O,O')(nia-N)(ACN)] (5), [Cu(mef-O)(mef-O,O')(nia-N)(EtOH)] (6) and [Cu(mef-O)(mef-O,O')(nia-N)(ACN)] (7) containing a molecule of relevant solvent as ligand in their primary crystal structure (tolf = tolfenamate, meclf = meclofenamate, mef = mefenamate, nia = nicotinamide, EtOH = ethanol, MeOH = methanol, ACN = acetonitrile). The structures of the complexes were determined by single-crystal X-ray analysis. The intermolecular interactions were studied by Hirshfeld surface analysis.