Background: Indication-based, in comparison to diagnoses-based, drug utilization studies in children are scarce in the literature.
Aim: To determine the adequacy of the prescriber's indications for specific drug treatments compared to the current literature in five different European countries; and to show the possibilities of performing indication-based drug utilization studies.
Design: a descriptive, cross-sectional, international study.
Introduction: Scarce information about comparative diagnostic and therapeutic patterns in paediatric outpatients of different countries is found in the literature.
Objective: To describe the similarities and differences observed in diagnosis and therapeutic patterns of paediatric patients of seven locations in different countries.
Design: Cross-sectional, prospective, international comparative, descriptive study.
Objective: To describe patterns observed in the treatment of acute otitis media (AOM) in several locations of five countries.
Patients And Methods: Cross-sectional, descriptive study. Random sample of 12,264 paediatric outpatients seen by paediatricians or general practitioners (GPs).
Background: Nucleoside analogues against herpes simplex virus (HSV) have been shown to suppress shedding of HSV type 2 (HSV-2) on genital mucosal surfaces and may prevent sexual transmission of HSV.
Methods: We followed 1484 immunocompetent, heterosexual, monogamous couples: one with clinically symptomatic genital HSV-2 and one susceptible to HSV-2. The partners with HSV-2 infection were randomly assigned to receive either 500 mg of valacyclovir once daily or placebo for eight months.