Publications by authors named "L Spadafora"

Patient-reported outcome measures (PROMs) are vital tools in cardiovascular disease (CVD) research and care, providing insights that complement traditional clinical outcomes like mortality and morbidity. PROMs capture patient experiences with CVD, such as quality of life, functional capacity, and emotional well-being, allowing clinicians to assess how interventions impact daily life. PROMs are integral to cardiovascular investigations as well as management, especially in chronic conditions and rehabilitation, where they inform on the impact of personalized care plans by tracking symptom progression and patient adherence.

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Background: Prompt reperfusion is critical for patients with ST-segment elevation myocardial infarction (STEMI) to improve outcomes. Yet, variability in regional healthcare delivery may influence treatment times and patient outcomes. We thus aimed at evaluating differences in management and outcomes of STEMI patients across Northern, Central, and Southern Italy, focusing on time-dependent reperfusion and in-hospital logistics.

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All recent guidelines on cardiovascular prevention have highlighted the role of a healthy diet and lifestyle advocating an holistic approach to reduce the cardiovascular burden among the population. Despite these efforts, registries have reported that only a minority of healthcare professionals provide advice on diet and lifestyle, and, in most cases, counseling is suboptimal for several reasons. Cardiovascular benefits linked to lifestyle and nutrition seem to be underestimated by many patients and doctors.

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Article Synopsis
  • - Acute chest pain (ACP) leads to many Emergency Department visits worldwide, necessitating quick and accurate diagnoses to address various serious conditions like acute coronary syndrome and pulmonary embolism.
  • - Misdiagnosis can either prevent crucial medical interventions or result in unnecessary hospital admissions, putting a strain on healthcare resources.
  • - Coronary computed tomography angiography (CCTA) enhances diagnostic accuracy for ACP, helping doctors effectively assess patients, as illustrated through a clinical case showing its critical role in identifying unclear symptoms.
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  • Platelets have a significant impact on aortic stenosis (AS) and patients undergoing transcatheter aortic valve implantation (TAVI), prompting an analysis of their indices in relation to AS stages.
  • In a study involving 220 TAVI patients, they were categorized into 5 AS stages based on cardiac damage, revealing a correlation between higher mean platelet volume (MPV) and advanced AS staging, as well as lower hemoglobin levels.
  • The findings indicate that while MPV and immature platelet fraction (IPF) show variations across stages, only MPV and body mass index (BMI) were significant predictors of higher AS staging in the logistic regression analysis.
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