DIABETES MELLITUS AND COVID-19: TODAY'S CHALLENGES.

Рatients with diabetes have more complications and higher mortality from COVID-19. This is due to the fact that diabetes impairs the immune response. Hyperglycemia causes a violation of the immune response, which in turn cannot control the spread of pathogenic microorganisms and therefore patients with diabetes are more susceptible to infections.

Special Considerations in the Systematic Psychosocial Screening of Youth with Type 1 Diabetes.

Objective: The American Diabetes Association recommends psychosocial screening for individuals with type 1 diabetes (T1D). The purpose of this study is to present (a) several high priority decisions that program developers may encounter when building a new psychosocial screening program and (b) both the screening development process and results of one mental health screening program within a multidisciplinary pediatric diabetes clinic, with particular emphasis on parent-youth screening agreement and changes to elevation status over time.

Methods: Youth with T1D ages 12-17 and parents of youth with T1D ages 8-17 were administered mental health screeners as a part of outpatient diabetes visits over a 1-year period.

Evidence of insulin-like growth factor binding protein-3 proteolysis during growth hormone stimulation testing.

Objectives: The ternary complex is composed of insulin-like growth factor (IGF)-I, IGF binding protein (IGFBP)-3 and acid labile subunit (ALS). Growth hormone (GH) promotes IGFBP-3 proteolysis to release free IGF-I, ALS, and IGFBP-3 fragments. Our aim was to determine whether elevated GH levels during GH stimulation testing would trigger IGFBP-3 proteolysis.

Nutrient intake in community-dwelling adolescent girls with anorexia nervosa and in healthy adolescents.

Background: Adolescence is a common time for the onset of anorexia nervosa (AN), a condition associated with long-term medical and hormonal consequences.

Objective: The objective was to compare the nutrient intakes of community-dwelling girls with AN with those of healthy adolescents and to describe the associations between specific nutrient intakes and nutritionally dependent hormones.

Design: Nutrient intakes in 39 community-dwelling girls with AN and 39 healthy adolescents aged 12.

Effects of anorexia nervosa on clinical, hematologic, biochemical, and bone density parameters in community-dwelling adolescent girls.

Objective: Anorexia nervosa (AN) is an eating disorder that leads to a number of medical sequelae in adult women and has a mortality rate of 5.6% per decade; known complications include effects on hematologic, biochemical, bone density, and body composition parameters. Few data regarding medical and developmental consequences of AN are available for adolescents, in particular for an outpatient community-dwelling population of girls who have this disorder.