Publications by authors named "L Somma"
Background: Brain metastases (BMs) represent the most frequent brain tumors in adults. The identification of key prognostic factors is essential for choosing the therapeutic strategy tailored to each patient. Epilepsy can precede several months of other clinical presentations of BMs.
View Article and Find Full Text PDFResponse to Letter to the Editor: Thresholds based on bone mineral density for therapeutic decision-making in postmenopausal women and men older than 50 years old under glucocorticoid therapy.
María Lorena Brance María Silvia Larroudé Luis Fernando Somma Luis Agustín Ramirez Stieben Lucas R Brun
Reumatol Clin (Engl Ed)
February 2024
The Florida State Collection of Arthropods (FSCA) is one of the largest and most valuable insect collections in the United States with more than twelve million curated specimens. The order Mecoptera currently comprises over 800 extant described species in nine extant families. The FSCA houses type material in the families Bittacidae, Panorpidae, and Panorpodidae.
View Article and Find Full Text PDFArticle Synopsis
- * A working group of experts from Argentina conducted systematic reviews, finding that many clinical trials did not specify BMD thresholds, while patients' T-scores mostly ranged from -1.6 to -2.0.
- * The expert panel agreed that a T-score of ≤-1.7 is the most suitable threshold for treatment in postmenopausal women and men over 50 on GC therapy, although other fracture risk factors should also be considered.
Article Synopsis
- The study aimed to create a framework for healthcare professionals to effectively prevent and treat glucocorticoid-induced osteoporosis (GIO) in postmenopausal women and men aged 50 or older who are undergoing glucocorticoid therapy.
- The expert panel employed a structured approach (PICO) and used GRADE methodology for a systematic literature review, producing 17 recommendations and 8 general principles for evaluating and treating patients at risk of GIO.
- The guidelines emphasize the importance of monitoring bone health, managing lifestyle factors, and preventing fragility fractures, with the ultimate goal of maintaining or improving bone mineral density in affected patients.*