Publications by authors named "L Sirvan"

Objective: The purpose of this study was to determine the patterns of failure and prognostic factors for lymphovascular space invasion (LVSI)-positive endometrioid endometrial cancer (EC) patients in the setting of negative lymph nodes (LNs).

Materials And Methods: A multicenter, retrospective department database review was performed to identify LVSI-positive patients with disease surgically confined to the uterus at two gynecologic oncology centers in Turkey. Demographic, clinicopathological and survival data were collected.

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Article Synopsis
  • The study compared the outcomes of women with pure ovarian clear cell carcinoma (OCCC) arising from endometriosis versus those without endometriosis.
  • Among the 93 women analyzed, those with OCCC from endometriosis tended to be younger, had more early-stage disease, and showed a significantly better 5-year overall survival rate (74.1%) compared to women without endometriosis (46.4%).
  • The extent of cytoreductive surgery was found to be a crucial independent factor for recurrence-free and overall survival, suggesting that while endometriosis affects certain demographics, it does not impact the overall prognosis of pure OCCC.
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Background/aim: The vanishing cancer phenomenon was first reported in radical prostatectomy specimens in the absence of neo-adjuvant treatment. Reported cases are mostly well-differentiated and low-volume tumors. A similar entity was described for hysterectomy specimens of patients with biopsy proven endometrial cancer (EC).

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Uterine leiomyosarcomas (LMS) are rare malignancies with a poor prognosis. The incidence is reported to be 3-7/100.000 per year.

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Objectives: Various physiological and pathological conditions can induce significant variations in plasma concentrations of tumor markers, such as CA 19-9, which is present in the serum and amniotic fluid of pregnant women. Herein, we aimed to determine the clinical importance of maternal serum CA 19-9 levels in the diagnosis of neural tube defects (NTDs).

Material And Methods: A total of 100 women were included in this controlled cross-sectional study.

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