Publications by authors named "L Scurtu"
Article Synopsis
- - Cutaneous squamous cell carcinoma (cSCC) is a common skin cancer, with early recognition being crucial as delayed diagnosis can lead to more aggressive forms and surgical complications.
- - Bowen's disease (BD) is an early stage of cSCC that shows specific skin features, but histopathology is essential for accurate diagnosis and treatment planning.
- - Diagnosing precancerous conditions like vulvar and penile intraepithelial neoplasia (VIN and PeIN) can be complex, often requiring multiple biopsies and utilizing techniques like immunostaining and HPV testing to guide treatment options.
Introduction: Skin metastases arise in 10% of cancer patients, but standardized dermoscopy diagnostic criteria for skin metastases remain poor. This study's objective was to analyze the dermoscopy features of skin metastases from advanced systemic and cutaneous cancers.
Methods: A retrospective study on 715 dermoscopy images of skin metastases from 33 patients with various primary cancers (breast, ovary, melanoma, non-melanoma skin cancer, and chronic leukemia) attending two academic centers between 2013 and 2023 was performed.
Background: Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are skin-derived carcinomas. The literature strongly connects SCC with acquired immunosuppression. Current data regarding BCC's association with immunosuppressive comorbidities are vague.
View Article and Find Full Text PDFPlatelet-rich plasma (PRP) therapy has gained attention in the scientific field due to its potential regenerative effects and great benefit-risk ratio. This review extensively explores the most studied mechanisms of this therapy according to the etiopathogenesis of skin diseases: cellular proliferation, matrix formation, regulation of inflammation, angiogenesis, collagen synthesis, and the remodeling of new tissue. Moreover, it draws on newly reported and lesser-known effects of PRP: its anti-apoptotic effects, immunological suppression, decrease in melanin synthesis, anti-microbial effects, overexpression of miR-155, antioxidant effects, and their involved pathways.
View Article and Find Full Text PDFAn unusual case of a 52-year-old female with two metachronous melanomas is presented. An atypical fast-growing nodular melanoma appeared 18 months after the complete excision of an in situ melanoma and one month afterward a SARS-CoV-2 infection. Intra-nodal melanocytic proliferations were identified during lymph node assessment, raising important diagnostic and prognostic concerns.
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