Publications by authors named "L Scholz"
Background: Pneumocystis jirovecii pneumonia (PCP) is a serious opportunistic infection in people living with HIV (PWH) who have low CD4 counts. Despite its side effects, trimethoprim-sulfamethoxazole (TMP-SMX) is currently considered the primary treatment for PCP.
Objectives: The objectives of this study are to compare the efficacy (treatment failure and mortality) and tolerability (treatment change) of PCP treatment regimens with a frequentist network meta-analysis.
Article Synopsis
- Invasive pulmonary aspergillosis (IPA) is increasingly affecting critically ill ICU patients who lack traditional risk factors, complicating diagnosis due to histological evidence challenges.
- A study analyzed 202 patients across nine centers, comparing existing classification criteria (EORTC-MSG, FUNDICU, Asp-ICU) for diagnosing IPA and their effectiveness in identifying cases confirmed by histology.
- Findings revealed that EORTC-MSG was highly effective in patients with known risk factors, while the FUNDICU criteria's accuracy improved when including factors like ARDS and post-cardiac surgery complications, enhancing its predictive performance.
Introduction: Delirium is a frequent complication in critically ill patients and is associated with adverse outcomes such as long-term cognitive impairment and increased mortality. It is unknown whether there are sex-related differences in intensive care unit (ICU) delirium and associated outcomes. We aimed to assess sex-specific differences in short-term mortality following ICU-delirium.
View Article and Find Full Text PDFA 63-year-old woman with a history of acute myeloid leukemia followed by stem cell transplantation presented with acute heart failure. Transthoracic echocardiography revealed a preserved left ventricular ejection fraction with severe ventricular hypertrophy and signs of elevated filling pressures indicating infiltrative cardiomyopathy. She died from cardiac arrest due to cardiogenic shock.
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