Prenatal PM exposure and neurodevelopment at 2 years of age in a birth cohort from Mexico city.

Background: Recent studies have reported that air pollution exposure may have neurotoxic properties.

Objective: To examine longitudinal associations between prenatal particles less than 2.5 μm in diameter (PM) exposure and neurodevelopment during the first two years of children's life.

Longitudinal associations between blood lead concentrations lower than 10 microg/dL and neurobehavioral development in environmentally exposed children in Mexico City.

Objective: Increasing evidence suggests that 10 microg/dL, the current Centers for Disease Control and Prevention screening guideline for children's blood lead level, should not be interpreted as a level at which adverse effects do not occur. Using data from a prospective study conducted in Mexico City, Mexico, we evaluated the dose-effect relationship between blood lead levels and neurodevelopment at 12 and 24 months of age.

Methods: The study population consisted of 294 children whose blood lead levels at both 12 and 24 months of age were < 10 microg/dL; blood lead levels were measured by graphite furnace atomic absorption spectroscopy; Bayley Scales of Infant Development II were administered at these ages.

[Levels of plasmatic lead in children 8-10 years of age and its relation to changes in visual-motor system and balance].

Objective: To assess the association between blood lead concentrations and visual-motor coordination and equilibrium in school age children.

Material And Methods: In November-December 1998, a cross-sectional study was conducted among 255 children aged 8-10, who attended public schools in Sector 1 of the Oaxaca State Public Education Institute. Data were collected using the Frostig Evaluation of Visual Perception test and the equilibrium subscale of the Frostig Movement Skills Test Battery.

[Factors related to the blood lead level in children 6 to 30 months old in the Prospective Lead Study in Mexico City].

A majority of the sample of children (N = 160-121, ages 6-30 months) from the Mexico City Prospective Lead Study exceeds the lowest limit action level (10 micrograms/dl) of the Centers for Disease Control standards for childhood lead exposure. Over one-third of the sample at 18 months and 24 months exceeds the action level (15 micrograms/dl) for aggressive intervention. Diet plays an important role in regulating early childhood blood lead levels.

Prenatal and postnatal blood lead level and head circumference in children to three years: preliminary results from the Mexico City Prospective Lead Study.

Multiple regression modeling was used to explore the relationship between prenatal and postnatal blood lead levels and child head circumference in the first three years of life. Maternal blood lead at 36 weeks of pregnancy and cord blood lead were found to be inversely related to 6 month and 18 month head circumference, respectively. Child 12 month blood lead was inversely related to 36 month head circumference.