Effects of a multifactorial prevention trial of coronary heart disease on the seasonal variation of the incidence of major cardiovascular events.

Under the influence of a primary prevention trial of coronary heart disease carried out for 10 years (1971-1982) in male subjects aged 40 to 60 years at entry, the curves of the seasonal variation of the incidence of myocardial infarction, sudden death and stroke were changed. The most important reductions of the incidence of these events were registered in spring and in September. In the rest of the year the effect of the action becomes variable according to the month and to the particular major events.

Seasonal variations of serum cholesterol detected in the Bucharest Multifactorial Prevention Trial of Coronary Heart Disease. Ten years follow-up (1971-1982).

A group of 4800 men, aged fourty to sixty at entry, subjected to a multifactorial prevention trial of coronary heart disease for a ten-year period, showed spontaneous seasonal variations of serum cholesterol, characterized by increases in winter and decreases in summer. The authors discuss the relationship between the food changes and the seasonal variation of serum cholesterol values.

Prevalence of arterial hypertension in a collectivity of adolescents.

Arterial hypertension in adolescents was studied in a group of 899 school boys aged 15-18 years from the vocational school No. 48 of the Bucharest Transport Enterprise (ITB) and the secondary school No. 19 ITB.

Evolution of ischemic heart disease risk factors in "The Bucharest Multifactorial Preventive Trial of Coronary Heart Disease" after 15-year follow-up.

The paper presents the evolution of the levels of smoking, hypercholesterolemia, essential hypertension and obesity in the course of a prophylactic action carried out for 15 years (1971-1986) in a group of 5000 males aged 40-60 years. In the group still available after 15 years of follow up consisting of 2000 subjects, a decrease was obtained in the number of smokers, from 22.3% to 5.