Judging a book by its older adult cover: age-related expectations and parental preference for children's books.

Unlabelled: As they typically have limited direct contact, children's attitudes towards older adults have more opportunity to be shaped by other social influences such as their parents and children's literature. Children's books have been noted for their tendency to portray older adults in stereotypical ways and their tendencies to underrepresent older adults. We investigated how the portrayal of older adults as major versus supporting characters, as well as parents' age-related expectations were related to parental preference for children's books.

Household behavior and vulnerability to acute malnutrition in Kenya.

Anticipating those most at-risk of being acutely malnourished significantly shapes decisions that pertain to resource allocation and intervention in times of food crises. Yet, the assumption that household behavior in times of crisis is homogeneous-that households share the same capacity to adapt to external shocks-ostensibly prevails. This assumption fails to explain why, in a given geographical context, some households remain more vulnerable to acute malnutrition relative to others, and why a given risk factor may have a differential effect across households? In an effort to explore how variation in household behavior influences vulnerability to malnutrition, we use a unique household dataset that spans 23 Kenyan counties from 2016 to 2020 to seed, calibrate, and validate an evidence-driven computational model.

A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density.

SynGAP is a Ras/Rap GTPase-activating protein (GAP) that is a major constituent of postsynaptic densities (PSDs) from mammalian forebrain. Its α1 isoform binds to all three PDZ (PSD-95, Discs-large, ZO-1) domains of PSD-95, the principal PSD scaffold, and can occupy as many as 15% of these PDZ domains. We present evidence that synGAP-α1 regulates the composition of the PSD by restricting binding to the PDZ domains of PSD-95.