Background: The recurrence of transient myocardial ischemia is a frequent event in the course of acute myocardial infarction. Postinfarction angina develops more frequently after a non-Q wave infarction, and after effective thrombolysis; when uncontrolled by standard medical treatment, it is associated with an increased incidence of unfavorable cardiac events. Therapeutic strategies involve aggressive medical therapy, frequent use of early angiography, and mechanical coronary revascularization with bypass surgery or transluminal coronary angioplasty (PTCA).
View Article and Find Full Text PDFIt has been recently shown that preload reduction affects the pattern of left ventricular (LV) filling in a way that mimics those Doppler changes that have been associated with impaired LV diastolic function. In order to better relate changes of mitral flow velocity profile to changes of the diastolic properties of the ventricle, in 11 ischemic patients diastolic pressure-volume relations from micromanometer LV pressure and LV volume derived from Doppler and 2D-echocardiography were constructed before and after TNT (0.2 mg iv).
View Article and Find Full Text PDFDoppler left ventricular inflow time-velocity curves have been extensively used to evaluate left ventricular filling. The reproducibility of the technique, however, has been rarely assessed, its temporal variability being, presently, unknown. In order to define the temporal reproducibility of Doppler parameters of left ventricular filling, 10 normal subjects were studied at 3 different times (baseline, after 24 hours, and after 1 week).
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