[MANAGEMENT OF PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS IN THE PREPREGNANCY AND ANTENATAL PERIODS: CHALLENGES AND SOLUTIONS (REVIEW)].

Systemic lupus erythematosus (SLE) is a rare, multi-systemic chronic autoimmune disease characterized by hyperproduction of organ-specific autoantibodies to various components of the cell nucleus with the development of immuno-inflammatory damage of tissues and internal organs, predominantly affecting women, particularly those of childbearing age. Hence future pregnancy is one of the key issues of the modern rheumatology. The management of the SLE patient should include an effective risk assessment of the future pregnancy and stratification followed by an individualized antenatal care program.