Publications by authors named "L Sanchez-Garcia"
Article Synopsis
- * A study was conducted at a hospital in Querétaro, Mexico, analyzing cases of multiorgan donors diagnosed with brain death over a seven-year period, using statistical tools to assess the data.
- * Out of 83 brain-dead patients, 56 became donors, with family refusal being the main reason for exclusions; most donors were male, aged between 10-20 years, with severe traumatic brain injury cited as the leading diagnosis.
Article Synopsis
- In 2023, Europe raised concerns about rising severe neonatal infections due to a new lineage of echovirus 11 (E11), prompting an analysis of E11 cases in Spain from 2019 to 2023.
- Out of 1,288 samples, 103 were found to be E11-positive, but the detection rates and severity of infections among neonates did not significantly change after the new lineage appeared in June 2022.
- The findings suggest that the new lineage 1 is not responsible for increased neonatal infections, but the discovery of novel E11 recombinants linked to severe cases highlights the need for better monitoring and surveillance.
Article Synopsis
- - Corneal tissue is essential for restoring vision through transplantation, but there’s a significant shortage of available corneas, particularly in Mexico, which lags behind other countries in donation rates.
- - A study analyzed medical records of 185 cadaveric corneal donors in Querétaro, Mexico, focusing on various factors including age, cause of death, and serological health tests for viruses like HIV and COVID-19.
- - The results showed the average donor age was 56.34 years, predominantly male, with common causes of death including cardiogenic and hypovolemic shock; a small percentage were excluded due to positive viral testing.
Background: The Andean Altiplano hosts a repertoire of high-altitude lakes with harsh conditions for life. These lakes are undergoing a process of desiccation caused by the current climate, leaving terraces exposed to extreme atmospheric conditions and serving as analogs to Martian paleolake basins. Microbiomes in Altiplano lake terraces have been poorly studied, enclosing uncultured lineages and a great opportunity to understand environmental adaptation and the limits of life on Earth.
View Article and Find Full Text PDFClonal hematopoiesis, a condition in which acquired somatic mutations in hematopoietic stem cells lead to the outgrowth of a mutant hematopoietic clone, is associated with a higher risk of hematological cancer and a growing list of nonhematological disorders, most notably atherosclerosis and associated cardiovascular disease. However, whether accelerated atherosclerosis is a cause or a consequence of clonal hematopoiesis remains a matter of debate. Some studies support a direct contribution of certain clonal hematopoiesis-related mutations to atherosclerosis via exacerbation of inflammatory responses, whereas others suggest that clonal hematopoiesis is a symptom rather than a cause of atherosclerosis, as atherosclerosis or related traits may accelerate the expansion of mutant hematopoietic clones.
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