Publications by authors named "L Samalin"
Article Synopsis
- Bipolar disorder (BD) is a complex mental health condition, and researchers aimed to identify a neurodevelopmental phenotype (NDP) that contributes to its development and impacts clinical outcomes.
- By analyzing data from over 4,400 BD patients, they established nine specific clinical features that characterize this NDP, which are linked to poorer prognosis and treatment responses.
- The findings suggest that patients with a higher NDP load may have overlapping genetic factors with ADHD, indicating a potential shared biological basis for these disorders.
Objective: ESKALE is a French, multicentre, observational study of adults with treatment-resistant depression (TRD) treated with esketamine. This interim analysis describes baseline demographic and clinical characteristic evolution in patients included and treated from early access program to post-marketing launch.
Methods: Data were collected from medical records and included patient characteristics, disease history at esketamine initiation, use of neurostimulation, the patient's care pathway, and the number of antidepressant treatment lines prescribed prior to esketamine initiation.
Background: Nutrition is largely affected in bipolar disorder (BD), however, there is a lack of understanding on the relationship between dietary categories, BD, and the prevalence of metabolic syndrome. The objective of this study is to examine dietary trends in BD and it is hypothesized that diets with increased consumption of seafood and high-fiber carbohydrates will be correlated to improved patient outcomes, and a lower frequency of metabolic syndrome.
Methods: This retrospective cohort study includes two French cohorts.