Reduced adult stem cell fate specification led to eye reduction in cave planarians.

Eye loss occurs convergently in numerous animal phyla as an adaptation to dark environments. We investigate the cave planarian Girardia multidiverticulata (Gm), a representative species of the Spiralian clade, to study mechanisms of eye loss. We found that Gm, which was previously described as an eyeless species, retains rudimentary and functional eyes.

Reemergence of yellow fever in the state of São Paulo: the structuring role of surveillance of epizootics in non-human primates in a one health approach.

Objective: to present a comprehensive analysis of YF occurrence of in the state of São Paulo since its reemergence, and the ongoing process of structuring the surveillance of epizootics in non-human primates in a one health approach.

Methods: descriptive study of human cases and epizootics in non-human primates, structuring actions and the one health approach used in the state of São Paulo for yellow fever surveillance from 2000 to 2023.

Results: from 2000 to 2023, 679 human cases and 857 epizootics in NHPs confirmed for yellow fever were recorded.

Comparison of patients undergoing protected high risk percutaneous coronary intervention using either intravascular lithotripsy or rotational atherectomy.

Background: Treating heavily calcified vessels is a challenging task in patients with an impaired left ventricular ejection fraction. Percutaneous mechanical circulatory support (pMCS) is increasingly used in patients in high-risk percutaneous coronary intervention (HRPCI).

Methods: In this retrospective registry, we investigated 25 patients undergoing a protected HRPCI receiving either intravascular lithotripsy (IVL + pMCS;  = 11) or rotational atherectomy (RA + pMCS;  = 14).

A disposable, portable electrochemical immunosensor for rapid in situ detection of bovine tuberculosis.

This contribution describes the development of a simple, fast, cost-effective, and sensitive impedimetric immunosensor for quantifying bovine tuberculosis (TB) in bovine serum samples. The construction of the immunosensor involved immobilizing the purified protein derivative (PPD) of M. bovis onto a screen-printed electrode that was modified with gold nanoparticles (AuNPs) and a polypyrrole (pPy) film synthesized electrochemically.