Neighbourhood Effects Across Generations and the Reproduction of Inequality.

This paper analyses the enduring impact of neighbourhood deprivation on youth development, exploring multigenerational aspects often overlooked in existing research. I investigate how neighbourhood environments experienced across two generations impact youth outcomes, focussing on cognitive skills and socio-emotional behaviour. Using data from the 1958 National Child Development Study in the UK, this study employs a Regression with Residuals (RWR) design to comprehensively assess any long-lasting effects.

The impact of obesity on mitochondrial dysfunction during pregnancy.

Mitochondria play a central role in nutrient metabolism, besides being responsible for the production of adenosine triphosphate (ATP), the main source of cellular energy. However, the ATP production process is associated with the generation of reactive oxygen species (ROS), which excessive accumulation can cause mitochondrial dysfunction. This dysfunction, in turn, causes the accumulation of fatty acids in the adipose tissue, triggering a local inflammatory process that can evolve into systemic inflammation.

Effects of sunflower cake in lamb diets on meat quality and its fatty acid profile.

This study aimed to evaluate the effects of sunflower cake (SFC) levels (0, 7, 14, 21, and 28% dry matter) in the diet for feedlot lambs on meat quality and its fatty acid profile. Forty crossbreed non castrated hair lambs were fed with experimental diets through 70 days when they were slaughtered and a Longissimus lumborum section were evaluated for physicochemical quality and fatty acid profile. There were no effects of SFC levels (P > 0.

Phytoceutical Isoquercitrin and Ethanolic Extracts from Pequi (Caryocar coriaceum Wittm) Reverse Alcohol Withdrawal-Induced Anxiety in Adult Zebrafish (Danio rerio).

Pharmacotherapy in Alcohol Withdrawal Syndrome (AWS), which is a mental disorder, generally involves benzodiazepines due to their action via GABA, but their side effects, such as excessive sedation, mental confusion and risk of dependence, are considerable. It is important to investigate the anxiolytic potential of plants such as Caryocar coriaceum, due to the presence of secondary metabolic compounds, such as isoquercitrin, capable of promoting the reduction of anxiety during AWS. We evaluated the anxiolytic-like potential of ethanolic extracts from the leaves (EEPL) and pulp (EEPP) of C.

Antifungal susceptibility, clinical findings, and biofilm resistance of Fusarium species causing keratitis: a challenge for disease control.

Fusarium keratitis (FK) is an important clinical condition that can lead to blindness and eye loss, and is most commonly caused by the Fusarium solani species complex (FSSC). This study evaluated the susceptibility of planktonic cells and biofilms of FSSC (n = 7) and non-FSSC (n = 7) isolates obtained from patients with keratitis from a semi-arid tropical region to amphotericin B (AMB), natamycin (NAT), voriconazole (VRZ), efinaconazole (EFZ), and luliconazole (LCZ). Analysis of clinical data showed that trauma was the most common risk factor for FK patients.