Publications by authors named "L S Zvekotkina"

In some cases radiodiagnosis of osteogenic sarcoma is associated with some difficulties resulting from a variety of its x-ray picture. The main factor that influences the x-ray manifestations of osteogenic sarcoma, is a neoplastic bone formation which reflects the morphological essence of this tumor. Other signs depend on a tumor site in one or another anatomical part of the tubular bone, on rates and type ot tumor growth.

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Comparative analysis of the results of radio- and scintigraphic investigation of 101 patients with thyroid cancer (TC) metastases to the bones has shown the appropriateness of combined diagnosis at all stages of patients' examination. The use of osteoscintigraphy with 99mTc-phosphates with subsequent x-ray investigation and whole-body scintigraphy with 131I contributes to early and more complete diagnosis of TC skeletal metastases. Iodine accumulation in TC bone metastases depends on the morphological structure of a tumor, the presence of functioning thyroid tissue and the level of iodine in the patient's body at the time of examination.

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Teletherapy or radiotherapy combined with 131I for thyroid cancer metastases to the bones caused the development of bone reparation in 70%, in 17% the picture remained unchanged; signs of further tumor growth were observed in 13%. An early x-ray sign of therapeutic efficacy was the decreased soft tissue component of a metastatic tumor 3-5 mos after the initiation of therapy. Disease stabilization was observed in 2.

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General principles of management of localized small-cell lung cancer were developed using the experience of treatment of 300 cases of the disease. Tumor extent should be assessed according to the TNM classification. The effectiveness of surgery + radiation as a first component of complex treatment was evaluated in a randomized study which included 71 patients.

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