Sources of intrapopulation variability in causative agents of nosocomial infection.

The mechanisms of heterogeneity of S. aureus and P. aeruginosa populations of pathological foci in patients with wound, traumatic, and burns infections were studied.

[Interpopulation variability of Staphylococcus aureus].

The comparative study of 830 hospital and 181 extrahospital S. aureus strains has revealed the existance of the interpopulation (group, geographic) variability of this species. Hospital strains differ from those inhabiting other places by the composition of phago- and resistovars, greater resistance to antibiotics, antiseptic and disinfecting agents, the inhibiting action of antagonist, as well as by pronounced antagonistic activity.

[Antibiotic resistance of Pseudomonas aeruginosa strains isolated from patients with infected burns].

Sensitivity to 15 drugs of 248 P. aeruginosa strains isolated from patients with infected burns was studied by the method of agar dilution. All of the strains were resistant to polymyxin M, ceporin, erythromycin and oleandomycin.