Publications by authors named "L S Toh"

People in Australia have access to different influenza vaccines, but may be unaware of their options and features. Preference studies for differentiated influenza vaccines including cell-based vaccines are limited, particularly in Australia. This study investigated which influenza vaccine attributes people in Australia value using a discrete choice experiment (DCE).

View Article and Find Full Text PDF
Article Synopsis
  • * In the study, 20 volunteers ingested caffeine through different sources while their blood was collected via DBS to monitor pharmacokinetics and assess how genetics affect caffeine metabolism.
  • * Results showed feasibility in collecting pharmacokinetic data in-flight, revealing varying metabolism rates among participants, particularly influenced by gender and contraceptive use, with significant differences observed in caffeine absorption based on the consumed source.
View Article and Find Full Text PDF

Background: Unplanned reattendances (UR) are an important quality indicator in the emergency department (ED). Understanding the risk factors associated with UR can aid clinicians in optimizing the allocation of time and resources, as well as targeted counselling for this specific group of patients. In this study, we aimed to compare patient characteristics between children who attended a pediatric emergency department (ED) with unplanned reattendances (UR) and those without UR.

View Article and Find Full Text PDF

Aposematic coloration offers an opportunity to explore the molecular mechanisms underlying canalization. In this study, the role of epigenetic regulation underlying robustness was explored in the aposematic coloration of the milkweed bug, () and (), which encode components of the Polycomb repressive complex 1 (PRC1) and PRC2, respectively, and , which encodes a component of the PRC2.2 subcomplex, were knocked down in the fourth instar of .

View Article and Find Full Text PDF

Spaceflight presents significant challenges to the physiological state of living organisms. This can be due to the microgravity environment experienced during long-term space missions, resulting in alterations in muscle structure and function, such as atrophy. However, a comprehensive understanding of the adaptive mechanisms of biological systems is required to devise potential solutions and therapeutic approaches for adapting to spaceflight conditions.

View Article and Find Full Text PDF