Publications by authors named "L S Stilgren"
Article Synopsis
- Two patients had stress fractures in their legs, and doctors looked into possible reasons for this, like bone conditions or cancer.
- They found that the medicine methotrexate (MTX) might be linked to these unusual fractures, with over 80 cases reported.
- Stopping MTX could help with healing, but overall, the benefits of using MTX for treating certain diseases are considered greater than the risks of bone issues.
Purpose: The preferred nuclear medicine method for identification of hyperfunctioning parathyroid glands in hyperparathyroidism (HPT) develops continuously in relation to the technological progress. Diagnostic methods based on PET/CT have during recent years evolved with new tracer possibilities competing with traditional scintigraphic methods. This investigation is a head-to-head comparison of Tc-99m-sestamibi SPECT/CT gamma camera scintigraphy (sestamibi SPECT/CT) and C-11-L-methionin PET/CT imaging (methionine PET/CT) for preoperative identification of hyperfunctioning parathyroid glands.
View Article and Find Full Text PDFIntroduction: The aim of this study was to investigate if the flash glucose level monitoring system (FGM) is better than traditional self-monitoring of blood glucose level (SMBG) in helping patients in the outpatient clinic control their blood glucose and improve glycaemic control measured by the concentration of glycated haemoglobin (HbA1c).
Methods: This was an observational real-life study based on data retrieved from a regional diabetes database and conducted in patients with Type 1 diabetes. HbA1c levels at baseline, and at six, nine and 12 months were compared in and between two groups counting 128 patients each.
Wnt signaling plays a pivotal role in maintaining bone mass. Secreted pathway modulators such as sclerostin (SOST) and Dickkopfs (DKKs) may influence bone mass inhibiting the canonical Wnt pathway. We evaluated whether bone protein content of secreted Wnt antagonists is related to age, bone mass, and strength in postmenopausal osteoporosis.
View Article and Find Full Text PDFObjective: To investigate the long term effect of hormone replacement therapy on cardiovascular outcomes in recently postmenopausal women.
Design: Open label, randomised controlled trial.
Setting: Denmark, 1990-93.