Publications by authors named "L S Segers"

Background: Alterations in regional brain microcirculation have not been well studied in patients with sepsis. Regional brain microcirculation can be studied using contrast-enhanced brain ultrasound (CEUS) with microbubble administration.

Methods: CEUS was used to assess alterations in regional brain microcirculation on 3 consecutive days in 58 patients with sepsis and within 24 h of intensive care unit admission in 10 aged-matched nonseptic postoperative patients.

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Article Synopsis
  • - Hypoxia induces various breathing behaviors, notably gasping, which helps improve blood flow and coordination between heart and lungs by altering breathing patterns and pressures in the body.
  • - The study tested if gasps during hypoxia are amplified by a specific circuit in the brain responsible for breathing and if this signal spreads to other areas involved in respiratory control.
  • - Results showed that changes in neuron activity and connectivity in brainstem circuits support the idea that these areas work together to enhance breathing efforts during hypoxia, leading to gasping as a lifesaving reflex.
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Environmental monitoring is essential for safeguarding the health of our planet and protecting human health and well-being. Without trust, the effectiveness of environmental monitoring and the ability to address environmental challenges are significantly compromised. In this paper, we present a sensor platform capable of performing authenticated and trustworthy measurements, together with a lightweight security protocol for sending the data from the sensor to a central server anonymously.

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Hypoxia can trigger a sequence of breathing-related behaviors, from tachypnea to apneusis to apnea and gasping, an autoresuscitative behavior that, via large tidal volumes and altered intrathoracic pressure, can enhance coronary perfusion, carotid blood flow, and sympathetic activity, and thereby coordinate cardiac and respiratory functions. We tested the hypothesis that hypoxia-evoked gasps are amplified through a disinhibitory microcircuit within the inspiratory neuron chain and a distributed efference copy mechanism that generates coordinated gasp-like discharges concurrently in other circuits of the raphe-pontomedullary respiratory network. Data were obtained from 6 decerebrate, vagotomized, neuromuscularly-blocked, and artificially ventilated adult cats.

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The computer vision community has paid much attention to the development of visible image super-resolution (SR) using deep neural networks (DNNs) and has achieved impressive results. The advancement of non-visible light sensors, such as acoustic imaging sensors, has attracted much attention, as they allow people to visualize the intensity of sound waves beyond the visible spectrum. However, because of the limitations imposed on acquiring acoustic data, new methods for improving the resolution of the acoustic images are necessary.

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