Publications by authors named "L S Ranganathan"
First clinical post-approval, observational study to assess clinical safety and effectiveness of brivaracetam sustained-release formulation in real-life settings of India: BEAM study.
Lakshmi Narasimhan Ranganathan Girish Kulkarni Ashutosh Kakkad Krishnaprasad Korukonda Narendra Chouksey
Seizure
January 2025
Purpose: Brivaracetam (BRV) sustained-release (SR) tablets have recently been approved to treat focal seizures in India. SR formulations enhance patient adherence and quality of life (QoL). We assessed safety and effectiveness of BRV-SR for epilepsy management in Indian real-life settings.
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- Stiff-person syndrome (SPS) is a rare disorder that makes your muscles really stiff and causes problems with movement, especially in the trunk and close muscles.
- There are different types of SPS, like classic SPS with widespread stiffness and partial SPS which affects just some limbs.
- A young man showed signs of SPS with a forward-leaning posture and involuntary movements, and doctors used tests like MRI and blood work to confirm the diagnosis and treat him.
Article Synopsis
- Varicella zoster virus (VZV) can lead to serious neurological conditions, either as complications during initial infection or when the virus reactivates, with better outcomes if diagnosed early and treated with antiviral drugs.
- In a study involving 30 unvaccinated participants, VZV DNA was found in one case while anti-VZV IgG was present in a significant majority, highlighting varied clinical presentations such as meningitis and altered sensorium.
- Routine testing for both VZV DNA and anti-VZV IgG in cerebrospinal fluid (CSF) is essential to improve early detection and reduce complications from VZV reactivation.
SummaryShapiro's syndrome is a rare neurological disease. The triad of Shapiro's syndrome includes episodes of hyperhidrosis, hypothermia and complete/partial agenesis of the corpus callosum. We report a case of a young male who had episodic chills, increased sweating and fatigue.
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