Publications by authors named "L S Novaes"
Purpose: This updated systematic review and meta-analysis aims to evaluate the impact of a birthing ball (BB) exercises on low-risk parturients during labor, offering a more comprehensive understanding through a larger sample size, robust analysis, and focus on relevant endpoints that were underexplored in previous studies due to limited data.
Methods: We searched PubMed, Embase, Scopus, and Cochrane Central for randomized controlled trials (RCTs) comparing BB (also named Swiss ball) exercises with no intervention or standard care in parturients undergoing low-risk labor. Risk ratios (RR) and mean differences (MD) were calculated using a random-effects model.
Article Synopsis
- Erectile dysfunction (ED) can occur in men who have had bilateral nerve-sparing surgery, with corporo-venocclusive dysfunction (CVOD) being a primary cause of permanent ED after radical prostatectomy (RP).
- A study examined comorbidity factors linked to CVOD in men without prior ED who underwent RP, finding significant associations with increased age and obstructive sleep apnea (OSA).
- The research highlights that comorbidities, particularly OSA, influence recovery of erectile function post-surgery; however, the findings may not apply broadly to all patients, as the study focused on men already seeking treatment for ED.
Article Synopsis
- Seed priming with Ascophyllum nodosum L. seaweed extract enhances the physiological quality and vigor of soybean seedlings, although more research is needed on optimal use protocols.
- Priming doses of 0 to 5 mL kg seed-1 for 15 minutes were tested, revealing that 5 mL kg-1 led to significant increases in shoot and root biomass without affecting germination rates.
- The study found an 18% increase in shoot dry matter with the highest ANE dose, and while some responses varied, the ANE improved the chlorophyll index, indicating better overall growth potential for soybeans.
Incorporation of C(sp)-F bonds in biologically active compounds is a common strategy employed in medicinal and agricultural chemistry to tune pharmacokinetic and pharmacodynamic properties. Due to the limited number of robust strategies for C(sp)-H fluorination of complex molecules, time-consuming syntheses of such fluorinated analogs are typically required, representing a major bottleneck in the drug discovery process. In this work, we present a general and operationally simple strategy for site-specific β-C(sp)-H fluorination of amine derivatives including carbamates, amides, and sulfonamides, which is compatible with a wide range of functional groups including -heteroarenes.
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