RSM optimization studies for cadmium ions adsorption onto pristine and acid-modified kaolinite clay.

Clay has been reported as an active absorbent for the removal of toxic heavy metals from aqueous medium. In this study, pristine and acid modified kaolinite clays (PKC and AMKC) were prepared, characterized using various analyses, and tested for Cd ion adsorption from textile industry wastewater. After acid modification, the specific surface area of clay increased from 84.

[ISO 9001: 2015 certification of all research activities of a university hospital center].

Introduction: In France, the number of hospitals involved in clinical research and committed to a quality approach is increasing. The objective of such approaches is to ensure the safety of patients involved in research projects by improving quality.

Objective: The University Hospital of Amiens has chosen to certify all its clinical research activities in the same scope according to the ISO 9001: 2015 standard.

Betulin, a Newly Characterized Compound in Bark, Is a Multi-Target Protein Kinase Inhibitor.

The purpose of this work is to investigate the protein kinase inhibitory activity of constituents from stem bark. Column chromatography and NMR spectroscopy were used to purify and characterize betulin from an ethyl acetate soluble fraction of acacia bark. Betulin, a known inducer of apoptosis, was screened against a panel of 16 disease-related protein kinases.

Current Status of Endoplasmic Reticulum Stress in Type II Diabetes.

The endoplasmic reticulum (ER) plays a multifunctional role in lipid biosynthesis, calcium storage, protein folding, and processing. Thus, maintaining ER homeostasis is essential for cellular functions. Several pathophysiological conditions and pharmacological agents are known to disrupt ER homeostasis, thereby, causing ER stress.

Potential Roles of Endoplasmic Reticulum Stress and Cellular Proteins Implicated in Diabesity.

The role of the endoplasmic reticulum (ER) has evolved from protein synthesis, processing, and other secretory pathways to forming a foundation for lipid biosynthesis and other metabolic functions. Maintaining ER homeostasis is essential for normal cellular function and survival. An imbalance in the ER implied stressful conditions such as metabolic distress, which activates a protective process called unfolded protein response (UPR).