In patients with acute leukemia (AL), malignant cells and therapy modify the properties of multipotent mesenchymal stromal cells (MSCs) and their descendants, reducing their ability to maintain normal hematopoiesis. The aim of this work was to elucidate the alterations in MSCs at the onset and after therapy in patients with AL. The study included MSCs obtained from the bone marrow of 78 AL patients (42 AML and 36 ALL) and healthy donors.
View Article and Find Full Text PDFProbl Sotsialnoi Gig Zdravookhranenniiai Istor Med
July 2020
The qualitative functioning of any medical institution depends on both professional competence of its staff and document management. The contemporary society is moving towards e-document management. The topicality of investigation stems from necessity to give scientific rationale and put into practice modern information systems and electronic technologies in the activities of head nurses.
View Article and Find Full Text PDFProbl Sotsialnoi Gig Zdravookhranenniiai Istor Med
June 2009
Zh Nevropatol Psikhiatr Im S S Korsakova
April 1989
A total of 65 patients at the productive age and with a history of ischemic stroke were examined. Comprehensive clinical and electromyographic studies revealed mild and moderate motor disturbances and determined criteria of the prognosis of motor function recovery. Follow-up findings confirmed the validity of these prognostic criteria.
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