[Possible applications of rac-hopantenic acid in the treatment of anxiety and depressive disorders in patients with chronic cerebral ischemia].

Aim: To evaluate the efficacy and tolerability of rac-hopantenic acid (pantogam activ) in patients with mixed anxiety-depressive disorder and anxiety-depressive disorder with chronic cerebral ischemia.

Material And Methods: A total of 50 patients were examined (30 patients in the main group, 20 patients in the control one). All patients received standard therapy with SSRI antidepressants.

[The formation of clinical and functional remission during the treatment of non-psychotic depression with escitalopram (lenuxin)].

The results of this study showed a high frequency of clinical remission (45.26%) during therapy of 98 patients with non-psychotic depression with escitalopram (lenuxin). However, the majority of patients (81.

[The modern concept of remission in non-psychotic depressive disorders].

The modern concept of remission should take into account its multidimensional structure which includes the complex interaction between clinical (severity/nature of residual symptoms, types of clinical remission), subjective (social functioning and patient's assessment of their condition) and integrative (relapses) characteristics. Based on the study of 385 patients during pharmaco- and psychotherapy, it was shown that the leading role in this structure belongs to the clinical type of remission (full, mono-, poly-symptomatic remission and remission with the structure of minor depression) which, according to the dimensional approach, creates a continuum of states from the complete absence of any symptoms to subsyndromal depression. Subjective and integrative characteristics are determined by clinical types of remission.