Publications by authors named "L Ruiz-Ponsell"
Hepatitis E virus (HEV), shared by humans, domestic animals, and wildlife, is an emerging global public health threat. Because wild boars are a major reservoir of HEV, the new zoonotic interfaces resulting from wild boar population increase and synurbization significantly contribute to increasing the risk of zoonotic transmission of HEV. This study characterizes HEV strains of synurbic wild boars and assesses their relationship with sympatric human and domestic swine HEV strains.
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- This study focuses on creating a biocompatible, acellular graft from human pericardium for tissue engineering by using a decellularization process to mimic the natural extracellular matrix.
- The decellularization was achieved through enzymatic and hypertonic methods, with histological analyses confirming the absence of cells while maintaining ECM structural integrity.
- The results showed that the acellular graft retained key biomolecules and mechanical properties, indicating its potential for various clinical applications.
The processing and initial testing of a new human tissue preparation is described. Full-thickness Acellular Dermal Matrix (ftADM) is the extracellular matrix (ECM) obtained by decellularization of full-thickness human skin from cadaveric donors. The safety, stability and usability of the graft are discussed with respect to the results of the residual cellular content, maintenance of ECM components, and biomechanical properties.
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