The results of the corrective rehabilitation program on the gait of amateur athletes with long-term consequences of brain injury.

Objective: Aim: To study the results of the quality of life, the state of vestibular disorders and the nature of walking of amateur athletes with the consequences of a combat craniocerebral injury after rehabilitation treatment according to a correctional program.

Patients And Methods: Materials and Methods: The study was conducted on the basis of the Ukrainian Scientific Research Institute of Prosthetics in Kharkov. Under observation were 38 men aged 25-42 years with long-term consequences of a closed craniocerebral injury in the late long-term period.

EFFICACY OF RECREATIONAL PHYSICAL ACTIVITY FOR PERIMENOPAUSAL WOMEN WITH HYPERTENSION ONSET.

Objective: The aim: To examine the effect of the developed wellness program on hemodynamic indices and psychological state of perimenopausal women.

Patients And Methods: Materials and methods: The study involved 27 women aged 39 to 47 years. Inclusion criteria: recorded perimenopause, climacteric syndrome, history of episodic increase in blood pressure up to 140/85 or 150/90 mmHg.

IMPLEMENTATION OF THE POLISH-UKRAINIAN PROJECT "SELF-DIAGNOSIS OF BREAST CANCER IN YOUNG UKRAINIAN WOMEN" WITHIN THE FRAMEWORK OF THE RITA PROGRAM - CHANGES IN THE REGION AT THE KHARKIV STATE ACADEMY OF PHYSICAL CULTURE.

Objective: The aim: To prove the effectiveness and necessity of implementation of the Polish-Ukrainian project"Self-diagnosis of breast cancer in young Ukrainian women within the framework of the RITA program-changes in the region(on the example of the Kharkiv State Academy of PhysicalCulture).

Patients And Methods: Materials and methods: 200 people took part in the study: 100 students and 100 lecturers and employees of the Kharkov State Academy of Physical Culture, attended lectures on epidemiology and prevention, risk factors and clinical features of breast cancer; took part in practical exercises on visual methods of breast cancer screening and the formation of self-examination skills. Each participant in the project was tested at the beginning and at the end of training, the tests included 20 questions about risk factors and clinical signs of breast cancer and an algorithm for its self-examination.

Formulation development of anti-stress compressed lozenges using a fractional factorial Latin cube design and ANOVA approach.

The aim of this work was to develop anti-stress compressed lozenges containing 100 mg of glycine and 250 mg of magnesium citrate obtained by the direct compression method. To choose optimal excipient composition providing the sufficient pharmaco-technical properties of the tablet blend, mechanical strength of tablets and non-disintegrating, slow-dissolving behavior of compressed lozenges during sucking, 27 experimental formulations according to fractional factorial Latin cube design were prepared and tested. The excipients used in the study were: Mannogem® EZ, Cellactose® 80 and GalenIQ 721 (fillers); Plasdone S-630, Kollidon® 90 F and Avicel® PH-101 (dry binders); Metolose® 90SH-4000SR and guar gum (gel-forming binders); PRUV®, Neusilin® US2, and Compritol® 888 CG ATO (antifriction excipients).

Development and uniformity evaluation of low-dose medicated chewing gums prepared by compression method.

The aim of this work was to develop medicated chewing gums (MCGs) containing 10 mg of lysozyme hydrochloride (LH) and 20 mg of ascorbic acid (AsA) obtained by the compression method with Health in Gum® (HiG®) PWD 01 as a compressible gum base. Because of a low content of active ingredients, it was essential to choose the way of adding them to the tableting mass and evaluate their distribution homogeneity in the dosage units. The blends for compression were prepared by two methods: the first one was simple mixing of all components; the second one included the step of wet granulation of a three-component mixture - LH, sucralose and a taste additive.