Publications by authors named "L Rousseau"

Survival analysis is critical in many fields, particularly in healthcare where it can guide medical decisions. Conventional survival analysis methods like Kaplan-Meier and Cox proportional hazards models to generate survival curves indicating probability of survival v. time have limitations, especially for long-term prediction, due to assumptions that all instances follow a general population-level survival curve.

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  • COVID-19 triage protocols are developed to manage resource shortages in ICUs and have sparked ethical debates, particularly regarding potential biases against certain groups based on age, frailty, or perceived social value.
  • The online Democratic Deliberation conducted in May and June 2022 in Quebec and Ontario aimed to gather public opinions on acceptable considerations and values that should guide these protocols.
  • Analysis revealed three main themes: the need for public acceptance of the protocols, essential considerations to include in triage decisions, and conditions that could enhance acceptance, with participants generally favoring prioritization based on survival prognosis and advocating for structured decision-making to reduce subjectivity.
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  • * The EU recently lowered the acceptable limit of CAP in animal tissues for human consumption from 0.30 µg/kg to 0.15 µg/kg, and the kits were validated according to the latest European regulations.
  • * The kits showed good performance with low false negative rates (≤ 5%) and reasonable false positive rates, making them suitable for both aquaculture and meat products at the same detection capability.
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Allogeneic hematopoietic cell transplantation (allo-HCT) presents a potentially curative treatment for hematologic malignancies yet carries associated risks and complications. Continuous research focuses on predicting outcomes and identifying risk factors. Notably, the influence of CD34+ cell dose on overall survival (OS) has been the subject of numerous studies yielding contradictory results.

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Over recent years, home health care has gained significant attention as an efficient solution to the increasing demand for healthcare services. Home health care scheduling is a challenging problem involving multiple complicated assignments and routing decisions subject to various constraints. The problem becomes even more challenging when considered on a rolling horizon with stochastic patient requests.

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